\tikzsetnextfilename{Rhythmuskontrolle-des-VHF}

    \begin{tikzpicture}[node distance=2cm]
    
    \node (about1) [about, text width=3.5cm] {\textbf{keine strukturelle Herzerkrankung}};
    \node (about2) [about, right of=about1, text width=3.5cm, xshift=6.25cm] {\textbf{strukturelle Herzerkrankung}};

    \node (comorbidity1) [comorbidity, below of=about2, yshift=-0.5cm, xshift=-2cm, text width=3.5cm] {Koronararterien-krankheit};
    \node (comorbidity2) [comorbidity, below of=about2, yshift=-0.5cm, xshift=2cm, text width=3.5cm] {Herzinsuffizienz};

    \draw [arrow] (about2) -- (comorbidity1);
    \draw [arrow] (about2) -- (comorbidity2);

    \node (therapy1) [therapy, below of=about1, xshift=-1.75cm, yshift=-3.5cm, text width=2.5cm] {Dofetilid*, Dronedaron, Flecainid**, Propafenon**, Sotalol*};
    \node (therapy2) [therapy, below of=about1, xshift=1.75cm, yshift=-3.5cm, text width=2.0cm] {Katheter-ablation};
    \node (therapy3) [therapy, below of=therapy1, yshift=-1cm, text width=2.5cm] {Amiodaron};

    \node (therapy4) [therapy, below of=comorbidity1, xshift=-1.25cm, yshift=-1cm, text width=2.25cm] {Dofetilid*, Dronedaron, Sotalol*};
    \node (therapy5) [therapy, below of=about2, yshift=-3.5cm, text width=2.0cm] {Katheter-ablation};
    \node (therapy6) [therapy, below of=comorbidity2, xshift=1.25cm, yshift=-1cm, text width=2.25cm] {Amiodaron, Dofetilid*};
    \node (therapy7) [therapy, below of=therapy4, yshift=-1cm, text width=2.25cm] {Amiodaron};

    \draw [arrow] (about1) -- (therapy1);
    \draw [dotted] (about1) -- (therapy2);
    \draw [arrow] (therapy1) -- (therapy3);
    \draw [arrow] (therapy3) -- (therapy2);
    \draw [arrow] (therapy1) -- (therapy2);

    \draw [arrow] (comorbidity1) -- (therapy4);
    \draw [arrow] (therapy4) -- (therapy7);
    \draw [arrow] (therapy7) -- (therapy5);
    \draw [arrow] (therapy4) -- (therapy5);
    \draw [arrow] (therapy6) -- (therapy5);
    \draw [dotted] (comorbidity1) -- (therapy5);   

    \draw [arrow] (comorbidity2) -- (therapy6);
    \draw [dotted] (comorbidity2) -- (therapy5);
    
    \end{tikzpicture}