\tikzsetnextfilename{Therapie-PJET}

    \begin{tikzpicture}[node distance=2cm]
    
    \node (about) [about, text width=5cm] {\textbf{postoperative \gls{jet}}};
    \node (therapy1) [therapy, below of=about, yshift=-1.5cm, text width=5cm, align=left] {
    \gls{iv} Amiodaron als Bolus
    \begin{itemize}[noitemsep,nolistsep,leftmargin=6mm]
      \item 1\,mg/kg über 10\,min
      \item Maximum: 5\,mg/kg über 60\,min
    \end{itemize}
    Beurteilung der Effizienz* alle 10\,min};
    \draw [arrow] (about) -- (therapy1);

    \node (therapy2) [therapy, below of=therapy1, yshift=-2.0cm, xshift=-6cm, text width=4cm] {keine weitere Amiodarongabe};
    \node (therapy3) [therapy, below of=therapy1, yshift=-2.0cm, xshift=3cm, text width=6cm, align=left] {
    \gls{iv} Amiodaron als Infusion
    \begin{itemize}[noitemsep,nolistsep,leftmargin=6mm]
      \item 5\,$\mu$g/kg/min 
      \item Maximum: 10\,$\mu$g/kg/min
    \end{itemize}
    Beurteilung der Effizienz*};
    \draw [arrow] ([yshift=-1.5cm]therapy1.west) -| node [pos=0.25, yshift=0.35cm, xshift=0.5cm, text width=3.5cm] {gute Effizienz*} (therapy2);
    \draw [arrow] ([yshift=-1.5cm]therapy1.east) -| node [pos=0.50, xshift=2.0cm, yshift=-0.5cm, text width=3.5cm] {keine bis mittelmäßige Effizienz*} (therapy3);

    \node (therapy4) [therapy, below of=therapy2, yshift=-1.5cm, text width=4cm] {temporäre Stimulation};
    \node (therapy5) [therapy, below of=therapy3, xshift=-1.5cm, yshift=-4cm, text width=9cm, align=left] {
    \begin{itemize}[noitemsep,nolistsep,leftmargin=6mm]
      \item Dexmedetomidin 1\,$\mu$g/kg Anfangsdosis, 1\,$\mu$g/kg/h Infusion
      \item Magnesium 25--50\,mg/kg über 10\,min
      \item Procainamid 7--10\,mg/kg über 30--45\,min oder 40--60\,$\mu$g/kg/min Infusion; Levelbestimmung nach 4\,h
      \item Esmolol 50--300\,$\mu$g/kg/min Infusion nach Anfangsdosis
    \end{itemize}
    Bewertung der Effizienz* nach jedem Schritt
    };
    \draw [arrow] (therapy2) -- node [pos=0.50, xshift=-1.50cm, text width=3.0cm] {gute Effizienz*} (therapy4);
    \draw [arrow] (therapy3.west) -- node [pos=0.50, xshift=1.75cm, yshift=-0.5cm, text width=3.0cm] {mittelmäßige Effizienz*} (therapy4);
    \draw [arrow] ([xshift=-1.5cm]therapy3.south) -- node [pos=0.50, xshift=2cm, text width=3.5cm] {keine Effizienz*} (therapy5);
    
    \node (therapy6) [therapy, below of=therapy5, yshift=-3cm, text width=6cm] {extrakorporale Membranoxygenierung in Betracht ziehen, Ablation};
    \draw [arrow] (therapy5) -- node [pos=0.50, xshift=2cm, text width=3.5cm] {keine Effizienz*} (therapy6);

    \node (therapy7) [therapy, fill=Blue200, left of=about, xshift=-4.5cm, yshift=-2.0cm, text width=6.25cm, align=left] {
    \textbf{Allgemeine Maßnahmen}
    \begin{itemize}[noitemsep,nolistsep,leftmargin=6mm]
      \item adäquate Sedation
      \item Normalisierung der Elektrolyte
      \item Reduktion der Inotropika
      \item Kühlung
    \end{itemize}
    Versuch der AAI/AOO-Stimulation
    };

    \end{tikzpicture}